Case Study

Metabolic Syndrome in Type 1 Diabetics: Prevalence and Clinicobiological Features

Y. Htira
Institut Natinal de Nutrition et de Technologies Alimentaires de Tunis, Tunisia
* Corresponding author
A. Mankai
Institut Natinal de Nutrition et de Technologies Alimentaires de Tunis, Tunisia
Z. Hadj Ali
Institut Natinal de Nutrition et de Technologies Alimentaires de Tunis, Tunisia
F. Ben Mami
Institut Natinal de Nutrition et de Technologies Alimentaires de Tunis, Tunisia
DOI icon 10.24018/ejmed.2021.3.5.990

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Submitted 2021-07-26
Published 2021-10-27

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Article Main Content

Background: Because of the world obesity epidemic, some type 1 diabetics exhibit clinical-biological features of metabolic syndrome. Few studies have investigated the association between this syndrome and this type of diabetes.

Aim: To estimate the prevalence of metabolic syndrome in type 1 diabetics and to study the relationship between this syndrome and the clinical-biological profile of these patients.

Methods: We carried out a cross-sectional study, involving type 1 diabetics, monitored at the National Institute of Nutrition in Tunis. All of these patients underwent a clinical examination and laboratory workup.

Results: We included 150 patients. The mean age of the patients was 31.25 ± 10.3 years. Women represented 54% of the patients. Abdominal obesity was found in 61.7% of women and 14.5% of men. The metabolic syndrome was found in 30.7% of patients, with a female predominance (48.1% vs. 10.1% in men, p <0.001). Comparing the two groups with and without metabolic syndrome, the latter was significantly correlated with sedentary lifestyle, daily insulin dose, hypertriglyceridemia, hypoHDL-cholesterolemia and arterial hypertension, but not correlated with the age of the patients, the duration of diabetes or the glycemic control.

Conclusion: This work reveals a high prevalence of metabolic syndrome in type 1 diabetics in whom it seems relevant to look for the components of this syndrome, each considered to be a cardiovascular risk factor in its own right.

Keywords: Diabetes, dyslipidemia, metabolic syndrome, overweight

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